Mark | Date Date | Title Title | |||
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30 Jun 2022 |
Test No. 251: Rapid Androgen Disruption Activity Reporter (RADAR) assay
The Rapid Androgen Disruption Activity Reporter (RADAR) Test Guideline describes an aquatic assay that utilizes transgenic Oryzias latipes (O. latipes, Japanese medaka) eleutheroembryos at day post hatch zero, in a multi-well format to detect... |
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17 Jun 2021 |
Test No. 250: EASZY assay - Detection of Endocrine Active Substances, acting through estrogen receptors, using transgenic tg(cyp19a1b:GFP) Zebrafish embrYos
The EASZY assay is a mechanism-based in vivo screening assay designed to detect endocrine active chemicals acting as agonist through estrogen receptors (ERs), by inducing the expression of the green fluorescent protein (GFP) driven by the cyp19a1b... |
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18 Jun 2021 |
Test No. 249: Fish Cell Line Acute Toxicity - The RTgill-W1 cell line assay
The RTgill-W1 cell line assay describes a 24-well plate format fish cell line acute toxicity test using the permanent cell line from rainbow trout (Oncorhynchus mykiss) gill, RTgill-W1. After 24 h of exposure to the test chemical, cell viability is... |
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18 Jun 2019 |
Test No. 248: Xenopus Eleutheroembryonic Thyroid Assay (XETA)
The purpose of the test is to measure the capacity of a chemical to activate or inhibit the transcription of a genetic construct (THb/ZIP-GFP X. laevis eleutheroembryos) either by binding to the thyroid hormone receptor or by modifying the amount of... |
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09 Oct 2017 |
Test No. 247: Bumblebee, Acute Oral Toxicity Test
This Test Guideline describes a method to assess effects of a test chemical on the phagocytotic activity of activated sludge containing protozoan organisms under defined conditions in the presence of different concentrations of the test chemical. The... |
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09 Oct 2017 |
Test No. 246: Bumblebee, Acute Contact Toxicity Test
This Test Guideline describes a method to assess effects of a test chemical on the phagocytotic activity of activated sludge containing protozoan organisms under defined conditions in the presence of different concentrations of the test chemical. The... |
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09 Oct 2017 |
Test No. 245: Honey Bee (Apis Mellifera L.), Chronic Oral Toxicity Test (10-Day Feeding)
This Test Guideline describes a method to assess effects of a test chemical on the phagocytotic activity of activated sludge containing protozoan organisms under defined conditions in the presence of different concentrations of the test chemical. The... |
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09 Oct 2017 |
Test No. 244: Protozoan Activated Sludge Inhibition Test
This Test Guideline describes a method to assess effects of a test chemical on the phagocytotic activity of activated sludge containing protozoan organisms under defined conditions in the presence of different concentrations of the test chemical. The... |
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29 Jul 2016 |
Test No. 243: Lymnaea stagnalis Reproduction Test
This Test Guideline is designed to assess effects of prolonged exposure to chemicals on the reproduction and survival of the hermaphrodite freshwater snail Lymnaea stagnalis (the Great Pond Snail). |
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29 Jul 2016 |
Test No. 242: Potamopyrgus antipodarum Reproduction Test
The Potamopyrgus antopodarumon reproduction test is designed to assess potential effects of prolonged exposure to chemicals on reproduction and survival of parthenogenetic lineages of the freshwater mudsnail Potamopyrgus antipodarum. Adult female P.... |
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28 Jul 2015 |
Test No. 241: The Larval Amphibian Growth and Development Assay (LAGDA)
This Test Guideline describes the Medaka Extended One Generation Test (MEOGRT), which exposes fish over multiple generations to give data relevant to ecological hazard and risk assessment of chemicals, including suspected endocrine disrupting... |
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04 Jul 2023 |
Test No. 240: Medaka Extended One Generation Reproduction Test (MEOGRT)
This Test Guideline describes the Medaka Extended One Generation Test (MEOGRT), which exposes fish over multiple generations to give data relevant to ecological hazard and risk assessment of chemicals, including suspected endocrine disrupting... |
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26 Sept 2014 |
Test No. 239: Water-Sediment Myriophyllum Spicatum Toxicity Test
This Test Guideline assesses the toxicity of chemicals on the growth of the rooted aquatic plants (Myriophyllum spicatum) growing in water-sediment system. |
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26 Sept 2014 |
Test No. 238: Sediment-Free Myriophyllum Spicatum Toxicity Test
This Test Guideline assesses the toxicity of chemicals on the growth of submerged aquatic plants Myriophyllum spicatum growing in a sediment-free test system. |
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26 Jul 2013 |
Test No. 237: Honey Bee (Apis Mellifera) Larval Toxicity Test, Single Exposure
This Test Guideline (TG) describes a honey bee brood acute toxicity test under laboratory conditions. The method aims at the determination of the lethal dose (72-h LD50) following single exposure of larvae to a chemical. On day 1 (D1) of the study ... |
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26 Jul 2013 |
Test No. 236: Fish Embryo Acute Toxicity (FET) Test
The test method described in this Test Guidelineis inteneded to determine the acute or letal toxicity of chemicals on embryonic stages of fish (Danio rerio). Newly fertilised zebrafish eggs are exposed to the test chemical for a period of 96 hrs ... |
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28 Jul 2011 |
Test No. 235: Chironomus sp., Acute Immobilisation Test
This Test Guideline describes an acute immobilisation assay on chronomids and is designed to complement existing Test Guidelines for chironomid chronic toxicity assays (TG 218, 219 and 233). The test method is based on TG 202: Daphnia sp. Acute ... |
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28 Jul 2011 |
Test No. 234: Fish Sexual Development Test
This Test Guideline describes an assay that assesses early life-stage effects and potential adverse consequences of putative endocrine disrupting chemicals (e.g. oestrogens, androgens and steroidogenesis inhibitors) on fish sexual development. In ... |
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23 Jul 2010 |
Test No. 233: Sediment-Water Chironomid Life-Cycle Toxicity Test Using Spiked Water or Spiked Sediment
This Guideline is designed to assess the effects of prolonged exposure of chemicals to the life-cycle of the sediment-dwelling freshwater dipteran Chironomus sp. First instar chironomid larvae are exposed to five concentrations of the test chemical ... |
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29 Jul 2016 |
Test No. 232: Collembolan Reproduction Test in Soil
This Test Guideline is designed for assessing the effects of chemicals on the reproduction of collembolans in soil. |
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- OECD Guidelines for the Testing of Chemicals
- OECD Guidelines for the Testing of Chemicals, Section 2
OECD Guidelines for the Testing of Chemicals, Section 2
Effects on Biotic Systems
The OECD Guidelines for the Testing of Chemicals is a collection of about 150 of the most relevant internationally agreed testing methods used by government, industry and independent laboratories to identify and characterise potential hazards of chemicals. They are a set of tools for professionals, used primarily in regulatory safety testing and subsequent chemical and chemical product notification, chemical registration and in chemical evaluation. They can also be used for the selection and ranking of candidate chemicals during the development of new chemicals and products and in toxicology research. This group of tests covers effects on biotic systems.
English Also available in: French
- ISSN: 20745761 (online)
- https://doi.org/10.1787/20745761
1 - 20 of 52 results
The Rapid Androgen Disruption Activity Reporter (RADAR) Test Guideline describes an aquatic assay that utilizes transgenic Oryzias latipes (O. latipes, Japanese medaka) eleutheroembryos at day post hatch zero, in a multi-well format to detect...
The EASZY assay is a mechanism-based in vivo screening assay designed to detect endocrine active chemicals acting as agonist through estrogen receptors (ERs), by inducing the expression of the green fluorescent protein (GFP) driven by the cyp19a1b...
The RTgill-W1 cell line assay describes a 24-well plate format fish cell line acute toxicity test using the permanent cell line from rainbow trout (Oncorhynchus mykiss) gill, RTgill-W1. After 24 h of exposure to the test chemical, cell viability is...
Test No. 248: Xenopus Eleutheroembryonic Thyroid Assay (XETA)
OECD
18 Jun 2019
The purpose of the test is to measure the capacity of a chemical to activate or inhibit the transcription of a genetic construct (THb/ZIP-GFP X. laevis eleutheroembryos) either by binding to the thyroid hormone receptor or by modifying the amount of...
Test No. 247: Bumblebee, Acute Oral Toxicity Test
OECD
09 Oct 2017
This Test Guideline describes a method to assess effects of a test chemical on the phagocytotic activity of activated sludge containing protozoan organisms under defined conditions in the presence of different concentrations of the test chemical. The...
Test No. 246: Bumblebee, Acute Contact Toxicity Test
OECD
09 Oct 2017
This Test Guideline describes a method to assess effects of a test chemical on the phagocytotic activity of activated sludge containing protozoan organisms under defined conditions in the presence of different concentrations of the test chemical. The...
Test No. 245: Honey Bee (Apis Mellifera L.), Chronic Oral Toxicity Test (10-Day Feeding)
OECD
09 Oct 2017
This Test Guideline describes a method to assess effects of a test chemical on the phagocytotic activity of activated sludge containing protozoan organisms under defined conditions in the presence of different concentrations of the test chemical. The...
Test No. 244: Protozoan Activated Sludge Inhibition Test
OECD
09 Oct 2017
This Test Guideline describes a method to assess effects of a test chemical on the phagocytotic activity of activated sludge containing protozoan organisms under defined conditions in the presence of different concentrations of the test chemical. The...
Test No. 243: Lymnaea stagnalis Reproduction Test
OECD
29 Jul 2016
This Test Guideline is designed to assess effects of prolonged exposure to chemicals on the reproduction and survival of the hermaphrodite freshwater snail Lymnaea stagnalis (the Great Pond Snail).
Test No. 242: Potamopyrgus antipodarum Reproduction Test
OECD
29 Jul 2016
The Potamopyrgus antopodarumon reproduction test is designed to assess potential effects of prolonged exposure to chemicals on reproduction and survival of parthenogenetic lineages of the freshwater mudsnail Potamopyrgus antipodarum. Adult female P....
This Test Guideline describes the Medaka Extended One Generation Test (MEOGRT), which exposes fish over multiple generations to give data relevant to ecological hazard and risk assessment of chemicals, including suspected endocrine disrupting...
This Test Guideline describes the Medaka Extended One Generation Test (MEOGRT), which exposes fish over multiple generations to give data relevant to ecological hazard and risk assessment of chemicals, including suspected endocrine disrupting...
Test No. 239: Water-Sediment Myriophyllum Spicatum Toxicity Test
OECD
26 Sept 2014
This Test Guideline assesses the toxicity of chemicals on the growth of the rooted aquatic plants (Myriophyllum spicatum) growing in water-sediment system.
Test No. 238: Sediment-Free Myriophyllum Spicatum Toxicity Test
OECD
26 Sept 2014
This Test Guideline assesses the toxicity of chemicals on the growth of submerged aquatic plants Myriophyllum spicatum growing in a sediment-free test system.
This Test Guideline (TG) describes a honey bee brood acute toxicity test under laboratory conditions. The method aims at the determination of the lethal dose (72-h LD50) following single exposure of larvae to a chemical. On day 1 (D1) of the study ...
Test No. 236: Fish Embryo Acute Toxicity (FET) Test
OECD
26 Jul 2013
The test method described in this Test Guidelineis inteneded to determine the acute or letal toxicity of chemicals on embryonic stages of fish (Danio rerio). Newly fertilised zebrafish eggs are exposed to the test chemical for a period of 96 hrs ...
Test No. 235: Chironomus sp., Acute Immobilisation Test
OECD
28 Jul 2011
This Test Guideline describes an acute immobilisation assay on chronomids and is designed to complement existing Test Guidelines for chironomid chronic toxicity assays (TG 218, 219 and 233). The test method is based on TG 202: Daphnia sp. Acute ...
Test No. 234: Fish Sexual Development Test
OECD
28 Jul 2011
This Test Guideline describes an assay that assesses early life-stage effects and potential adverse consequences of putative endocrine disrupting chemicals (e.g. oestrogens, androgens and steroidogenesis inhibitors) on fish sexual development. In ...
Test No. 233: Sediment-Water Chironomid Life-Cycle Toxicity Test Using Spiked Water or Spiked Sediment
OECD
23 Jul 2010
This Guideline is designed to assess the effects of prolonged exposure of chemicals to the life-cycle of the sediment-dwelling freshwater dipteran Chironomus sp. First instar chironomid larvae are exposed to five concentrations of the test chemical ...
Test No. 232: Collembolan Reproduction Test in Soil
OECD
29 Jul 2016
This Test Guideline is designed for assessing the effects of chemicals on the reproduction of collembolans in soil.